Important Information - MDR1 mutation~

HOME NUVET PLUS OUR DOGS IMPORTANT INFORMATION PUPPIES OLDER DOGS FOR SALE REFERENCES REFERENCES PAGE 2 AQHA HORSES BREAST CANCER GUEST BOOK

***** Many different drugs and drug classes have been reported to cause problems in Collies and other herding bred dogs that carry the MDR1 mutation.

Aussies and other herding types (Collies, Border Collies ans Shelties) can have certain drug sensitivities.

Aussies should never be given any type of drug below.

***** Please note Heartguard is on the list and can cause seizures in aussies.

***** Never give Heartguard to an Aussie, choose Interceptor instead.

Also note, not all vets are familiar with this list or the MDR1 mutation.

DRUG NO NO'S

Drugs that have been documented, or are strongly suspected to cause problems in dogs with MDR1 mutation:

* Ivermectin (antiparasitic agent) "Heartguard"
* Loperamide (Imodium; over the counter antidiarrheal agent)
* Doxorubicin (anticancer agent)
* Vincristine (anticancer agent)
* Vinblastine (anticancer agent)
* Cyclosporin (immunosuppressive agent)
* Digoxin (heart drug)
* Acepromazine (tranquilizer)
* Butorphanol (pain control)